Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197538 | 0.88 | CDK1 (0.34) | SLC6A2CDK1CCNB2CCNB1CDK2 | |
| SCHEMBL9197685 | 0.81 | PI4KA (0.49) | SLC6A2CDK1HTT | |
| SCHEMBL9194252 | 0.75 | PDE4A (0.64) | ADORA2AADORA1PDE4APDE4BPDE4C | |
| SCHEMBL9741377 | 0.74 | EGFR (0.36) | HTTHPGDSMN1; SMN2 | |
| SCHEMBL9193101 | 0.71 | LMNA (0.66) | ADORA2AADORA1HTTADORA2BNPC1 | |
| SCHEMBL9199457 | 0.71 | CYP1A2 (0.35) | SLC6A2 | |
| SCHEMBL9194028 | 0.69 | SLC6A2 (0.46) | SLC6A2HTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9848536 | 0.69 | SLC6A2 (0.46) | SLC6A2CDK2HTTNPC1HPGD | |
| SCHEMBL18379331 | 0.65 | CDK4 (0.54) | SLC6A2HTTHPGDRAB9A | |
| SCHEMBL9194494 | 0.64 | YTHDC1 (0.38) | CDK1CCNB2CCNB1CDK2CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1029968-C | Process for preparation of N-heteroaryl-purin-6-amines and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1995-10-11 | — | — | CN | disclosed |
| EP-0402752-B1 | N-heteroaryl-purin-6-amines, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5155098-A | Analgesics, anticonvulsants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5017578-A | N-heteroaryl-purin-6-amines useful as analgesic and anticonvulsant agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0402752-A1 | N-heteroaryl-purin-6-amines, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1990-12-19 | — | — | EP | disclosed |
| CN-1047866-A | The preparation method of N-heteroaryl-purine-6-amine and medicinal | HOECHST ROUSSEL PHARMA (US) | 1990-12-19 | — | — | CN | disclosed |