Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | EPHB3 | P54753 | 6/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303173 | 0.91 | POLB (0.46) | CYP1A2HPGDCYP2C19POLBNPC1 | |
| SCHEMBL28999700 | 0.86 | ATM (0.50) | ATMIRAK4 | |
| SCHEMBL18117491 | 0.86 | ATM (0.53) | CYP1A2HPGDCYP2C19POLBNPC1 | |
| SCHEMBL972387 | 0.85 | ALOX15 (0.53) | POLB | |
| SCHEMBL3429596 | 0.85 | NAMPT (0.42) | CYP1A2HPGDCYP2C19POLBNPC1 | |
| SCHEMBL28348101 | 0.85 | ATM (0.49) | POLBNPC1ATMRAB9AIRAK4 | |
| SCHEMBL12393703 | 0.85 | ATM (0.49) | ATMIRAK4 | |
| SCHEMBL973185 | 0.85 | ATM (0.69) | HPGDATMIRAK4 | |
| SCHEMBL31475430 | 0.85 | ATM (0.69) | HPGDATMIRAK4 | |
| SCHEMBL29199146 | 0.84 | ATM (0.48) | HPGDATMIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257530-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2011-10-12 | — | — | EP | claimed |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | claimed |
| EP-2257530-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | Bayer CropScience Aktiengesellschaft (DE) | 2010-12-08 | — | — | EP | claimed |
| WO-2009106234-A1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | WO | claimed |
| EP-2093216-A1 | Process for preparing substituted biphenylanilides | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | claimed |
| US-8350046-B2 | Method for manufacturing aryl carboxamides | BASF SE (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20110054183-A1 | Method For Manufacturing Aryl Carboxamides | BASF SE | 2011-03-03 | — | — | US | disclosed |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054183-A1 | Method For Manufacturing Aryl Carboxamides | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR3, CBR1 | CYP1A2 281/4885HPGD 2147/4885CYP2C19 921/4885 |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | DDT, PAH, THOP1 | CYP1A2 48/4885HPGD 1900/4885CYP2C19 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.