Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.34 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KIF5B | P33176 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741234 | 0.83 | CYP3A4 (0.59) | TSHRCYP3A4RECQLKDRRIPK2 | |
| SCHEMBL18235928 | 0.81 | GUCY1A1 (0.45) | TSHRCYP3A4RECQLGUCY1A1GUCY1B1 | |
| SCHEMBL8511557 | 0.80 | CYP3A4 (0.38) | TSHRCYP3A4RECQLKDRRET | |
| SCHEMBL126869 | 0.77 | TSHR (1.00) | TSHRCYP3A4RECQLKDRRIPK2 | |
| Potassium SCHEMBL30495500 | 0.76 | TSHR (0.96) | TSHRCYP3A4RECQLKDRRIPK2 | |
| Potassium SCHEMBL30495501 | 0.76 | TSHR (0.96) | TSHRCYP3A4RECQLKDRRIPK2 | |
| SCHEMBL28530092 | 0.76 | TSHR (0.96) | TSHRCYP3A4RECQLKDRRIPK2 | |
| SCHEMBL7574426 | 0.75 | CYP3A4 (0.33) | TSHRCYP3A4RECQLMAPK14GAA | |
| SCHEMBL21635494 | 0.74 | CYP3A4 (0.72) | TSHRCYP3A4RECQLKDRRIPK2 | |
| SCHEMBL459121 | 0.74 | CYP3A4 (0.67) | TSHRCYP3A4RECQLRIPK2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4923479-A | HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 1990-05-08 | — | — | US | claimed |
| US-5111472-A | Rhodamine dye, 540 to 570 nm | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5047559-A | Multistep Reaction Beginning With 3-Amino-4-Methylphenol | UNITED STATES DEPARTMENT OF ENERGY (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0269914-B1 | COMPOSITION AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR ON THE BASIS OF 3-(2',2',2'-TRIFLUORETHYL)AMINOPHENOL DERIVATIVES, AND 3-(2',2',2'-TRIFLUORETHYL)AMINOPHENOL DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-06-12 | — | — | EP | disclosed |
| US-4992560-A | Condensation of N-monoalkylated 3-amino-4-methylphenol with phthalic anhydride | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1991-02-12 | — | — | US | disclosed |
| US-4945176-A | Novel fluorinated laser dyes | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1990-07-31 | — | — | US | disclosed |
| US-4923479-A | HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 1990-05-08 | — | — | US | disclosed |
| WO-1988004166-A1 | HAIR DYEING OXIDISING AGENT AND PROCESS WITH 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES AND NEW 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES | WELLA AKTIENGESELLSCHAFT (DE) | 1988-06-16 | — | — | WO | disclosed |