SCHEMBL8511557

SCHEMBL8511557

Oc1ccc(F)c(NCC(F)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ ADRA2A P08913 1/20 0.37
▸ ADRA2B P18089 1/20 0.37
▸ ADRA2C P18825 1/20 0.37
▸ IL1B P01584 1/20 0.35
▸ NLRP3 Q96P20 1/20 0.35
▸ BACE1 P56817 2/20 0.33
▸ PTPN7 P35236 1/20 0.33
▸ DUSP3 P51452 1/20 0.33
▸ KIF11 P52732 1/20 0.33
▸ RET P07949 1/20 0.33
▸ KIF5B P33176 1/20 0.33
▸ KDR P35968 1/20 0.33
▸ ESR1 P03372 4/20 0.33
▸ ESR2 Q92731 2/20 0.33
▸ TYR P14679 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.32
▸ MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9741759 0.80 TSHR (0.62) CYP3A4TSHRRECQLRETKIF5B
SCHEMBL21635491 0.77 CYP3A4 (0.63) CYP3A4TSHRRECQLADRA2AADRA2B
SCHEMBL5512648 0.75 KIF11 (0.36) CYP3A4TSHRRECQLADRA2AADRA2B
SCHEMBL29440029 0.73 ESR1 (0.34) ESR1ESR2
SCHEMBL19849657 0.73 ESR1 (0.34) ESR1ESR2
SCHEMBL18827200 0.70 TRPM5 (0.50) IL1BNLRP3MEN1MAPTRAB9A
SCHEMBL2709499 0.70 ADRA2A (0.46) CYP3A4TSHRRECQLADRA2AADRA2B
SCHEMBL7159847 0.70 APP (0.43) RECQLKIF11ESR1ESR2KDM4E
SCHEMBL16280538 0.70 ADRA2A (0.38) CYP3A4TSHRRECQLADRA2AADRA2B
SCHEMBL2709623 0.69 PDK1 (0.44) TSHRKDM4EMEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11275265-B2 Control of illumination spectra for LCD displays MOLECULED LTD. (IL) 2022-03-15 — — US disclosed
US-10808127-B2 Color conversion with solid matrix films and green rhodamines MOLECULED LTD. (IL) 2020-10-20 — — US disclosed
US-10808127-B2 Color conversion with solid matrix films and green rhodamines MOLECULED LTD. (IL) 2020-10-20 — — US disclosed
US-10465110-B2 Rhodamine based salts StoreDot Ltd. (IL) 2019-11-05 — — US disclosed
US-10465110-B2 Rhodamine based salts StoreDot Ltd. (IL) 2019-11-05 — — US disclosed
US-10240042-B2 Photoluminescent compounds and uses thereof StoreDot Ltd. (IL) 2019-03-26 — — US disclosed
US-10240042-B2 Photoluminescent compounds and uses thereof StoreDot Ltd. (IL) 2019-03-26 — — US disclosed
US-10227492-B2 Modifications of the sol-gel films and production processes thereof StoreDot Ltd. (IL) 2019-03-12 — — US disclosed
US-10227492-B2 Modifications of the sol-gel films and production processes thereof StoreDot Ltd. (IL) 2019-03-12 — — US disclosed
US-10100197-B2 Rhodamine derivatives dyes and uses thereof StoreDot Ltd. (IL) 2018-10-16 — — US disclosed
US-20180057688-A1 RHODAMINE DERIVATIVES DYES AND USES THEREOF MOLECULED LTD. (IL) 2018-03-01 — — US disclosed
US-20180057689-A1 RHODAMINE DERIVATIVES DYES AND USES THEREOF StoreDot Ltd. (IL) 2018-03-01 — — US disclosed
US-20180057689-A1 RHODAMINE DERIVATIVES DYES AND USES THEREOF StoreDot Ltd. (IL) 2018-03-01 — — US disclosed
US-20180039131-A1 CONTROL OF ILLUMINATION SPECTRA FOR LCD DISPLAYS StoreDot Ltd. (IL) 2018-02-08 — — US disclosed
US-20180037738-A1 COLOR CONVERSION WITH SOLID MATRIX FILMS StoreDot Ltd. (IL) 2018-02-08 — — US disclosed
US-20180039131-A1 CONTROL OF ILLUMINATION SPECTRA FOR LCD DISPLAYS StoreDot Ltd. (IL) 2018-02-08 — — US disclosed
US-20180037738-A1 COLOR CONVERSION WITH SOLID MATRIX FILMS StoreDot Ltd. (IL) 2018-02-08 — — US disclosed
EP-2445969-B1 NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) 2014-08-27 — — EP disclosed
US-8735444-B2 Fluorinated rhodamines as photostable fluorescent dyes for labelling and imaging techniques MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2014-05-27 — — US disclosed
US-20120135459-A1 NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2012-05-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120135459-A1 NOVEL FLUORINATED RHODAMINES AS PHOTOSTABLE FLUORESCENT DYES FOR LABELLING AND IMAGING TECHNIQUES SNRPD1, SRSF6, DRD1 CYP3A4 3231/4885TSHR 1915/4885RECQL 472/4885
US-10240042-B2 Photoluminescent compounds and uses thereof MAPRE2, TYR, IK CYP3A4 978/4885TSHR 4048/4885RECQL 667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback