Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741973 | 0.87 | THRA (0.42) | ESR1ESR2THRAMMP1L3MBTL1 | |
| SCHEMBL9741976 | 0.86 | ESR1 (0.41) | ESR1ESR2THRAMMP1L3MBTL1 | |
| SCHEMBL8966583 | 0.75 | THRA (0.43) | ESR1ESR2THRA | |
| SCHEMBL9742252 | 0.72 | ESR1 (0.45) | ESR1ESR2THRAL3MBTL1 | |
| SCHEMBL9741860 | 0.72 | ESR1 (0.43) | ESR1ESR2THRAL3MBTL1 | |
| SCHEMBL8966124 | 0.69 | ESR1 (0.53) | ESR1ESR2L3MBTL1 | |
| SCHEMBL17765395 | 0.69 | PDE4D (0.42) | THRA | |
| SCHEMBL17773361 | 0.68 | HSD17B3 (0.35) | THRAL3MBTL1 | |
| SCHEMBL31235645 | 0.68 | NR5A1 (0.45) | TP53MAPT | |
| SCHEMBL1309184 | 0.66 | MAPT (0.40) | ESR1ESR2THRATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147880-A | Estrogenic and antiestrogenic activity | ELI LILLY AND COMPANY (US) | 1992-09-15 | — | — | US | disclosed |