Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966136 | 0.87 | ESR1 (0.56) | ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL8966131 | 0.85 | ESR1 (0.53) | ESR1ESR2 | |
| SCHEMBL8965856 | 0.71 | ESR1 (0.58) | ESR1ESR2 | |
| SCHEMBL8966114 | 0.69 | ESR1 (1.00) | ESR1ESR2 | |
| SCHEMBL18150401 | 0.69 | ESR1 (0.75) | ESR1ESR2 | |
| SCHEMBL9741966 | 0.69 | ESR1 (0.41) | ESR1ESR2L3MBTL1 | |
| SCHEMBL9571852 | 0.69 | ESR1 (0.54) | ESR1ESR2ALDH1A1L3MBTL1 | |
| SCHEMBL8966236 | 0.69 | ESR1 (0.53) | ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL8966586 | 0.66 | ESR1 (0.41) | ESR1ESR2DRD2DRD4DRD3 | |
| SCHEMBL7525411 | 0.66 | ESR1 (0.85) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524742-B1 | Benzo(a)fluorene compounds | LILLY CO ELI (US) | 1996-02-28 | — | — | EP | disclosed |