Sugi Predict

Sugi Predict / Compounds / SCHEMBL9741978

SCHEMBL9741978

SCHEMBL9741978

CNC(=O)N(O)CC1COc2ccc(Oc3ccccc3)cc2O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 18/20 1.00
▸ ALOX12 P18054 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9694733 0.96 ALOX5 (1.00) ALOX5ALOX12
SCHEMBL9695898 0.89 ALOX5 (0.80) ALOX5
SCHEMBL9618561 0.87 ALOX5 (1.00) ALOX5ALOX12
SCHEMBL9696815 0.85 ALOX5 (0.80) ALOX5ALOX12
SCHEMBL9695902 0.83 ALOX5 (0.77) ALOX5ALOX12
SCHEMBL9694802 0.83 ALOX5 (1.00) ALOX5ALOX12
SCHEMBL9696249 0.78 ALOX5 (0.80) ALOX5ALOX12
SCHEMBL9694749 0.78 ALOX5 (0.65) ALOX5
SCHEMBL9695886 0.77 ALOX5 (1.00) ALOX5ALOX12
SCHEMBL13696683 0.77 ALOX5 (1.00) ALOX5ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120758-A Treating allergic, inflammatory, cardiovascular, pulmonary, arthritic, cutaneous disorders CIBA-GEIGY CORPORATION (US) 1992-06-09 — — US disclosed