Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696815 | 0.89 | ALOX5 (0.80) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL9694733 | 0.87 | ALOX5 (1.00) | ALOX5ALOX12 | |
| SCHEMBL9694802 | 0.87 | ALOX5 (1.00) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL9695898 | 0.85 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL9741978 | 0.83 | ALOX5 (1.00) | ALOX5ALOX12 | |
| SCHEMBL9618561 | 0.83 | ALOX5 (1.00) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL9696249 | 0.83 | ALOX5 (0.80) | ALOX5ALOX12PTGS1PTGS2 | |
| SCHEMBL9695885 | 0.81 | ALOX5 (0.68) | ALOX5ALOX12 | |
| SCHEMBL9696456 | 0.78 | ALOX5 (0.65) | ALOX5 | |
| SCHEMBL9696408 | 0.75 | ALOX5 (0.62) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498770-A1 | Certain benzodioxole, benzodioxane and benzodioxepin derivatives | CIBA-GEIGY AG (CH) | 1992-08-12 | — | — | EP | disclosed |
| US-5120758-A | Treating allergic, inflammatory, cardiovascular, pulmonary, arthritic, cutaneous disorders | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |