Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | HTR1B | P28222 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215673 | 0.87 | HTR1A (0.45) | HTR1ADRD2HTR1DHTR1B | |
| Water SCHEMBL9739470 | 0.83 | HTR1A (0.45) | HTR1ADRD2HTR1DHTR1BSLC6A4 | |
| Hydrochloric Acid SCHEMBL9743101 | 0.80 | HTR1A (0.52) | HTR1ADRD2HTR1DHTR1BSLC6A4 | |
| SCHEMBL9207818 | 0.79 | HTR1A (0.43) | HTR1ADRD2SLC6A4HTR7HRH1 | |
| Water SCHEMBL9739270 | 0.78 | HTR1A (0.43) | HTR1ADRD2SLC6A4HTR7HRH1 | |
| SCHEMBL9213548 | 0.75 | PDE5A (0.37) | SLC6A4SLC6A3MEN1MAPK1KMT2A | |
| SCHEMBL9216130 | 0.74 | HTR1A (0.47) | HTR1ADRD2HTR1DHTR1BSLC6A4 | |
| SCHEMBL9216571 | 0.72 | PDE4D (0.49) | HTR1ADRD2HTR1DHTR1BSLC6A4 | |
| SCHEMBL9206815 | 0.71 | HTR1A (0.55) | HTR1ADRD2HTR1DHTR1BSLC6A4 | |
| Hydrochloric Acid SCHEMBL9740012 | 0.71 | PDE4D (0.48) | HTR1ADRD2HTR1DHTR1BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |