Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742172 | 1.00 | EGFR (0.43) | EGFRGABRA1GABRB2PTGS1PTGS2 | |
| SCHEMBL14283741 | 1.00 | EGFR (0.43) | EGFRGABRA1GABRB2PTGS1PTGS2 | |
| SCHEMBL27835934 | 0.86 | CYP3A4 (0.39) | EGFRTYRACHECYP3A4 | |
| SCHEMBL11126248 | 0.84 | EGFR (0.43) | EGFRGABRA1GABRB2PTGS1PTGS2 | |
| SCHEMBL9744031 | 0.84 | TYR (0.54) | TYRHTTALOX15ALOX5CYP3A4 | |
| SCHEMBL8413465 | 0.84 | PRKCI (0.56) | GABRA1GABRB2PTGS1PTGS2PRKCI | |
| SCHEMBL9744034 | 0.84 | TYR (0.54) | TYRHTTALOX15ALOX5CYP3A4 | |
| SCHEMBL6029153 | 0.80 | EGFR (0.43) | EGFRGABRA1GABRB2PTGS1PTGS2 | |
| SCHEMBL6029157 | 0.80 | EGFR (0.43) | EGFRGABRA1GABRB2PTGS1PTGS2 | |
| SCHEMBL8570848 | 0.79 | POLB (0.59) | PTGS1PTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |