Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029157 | 1.00 | EGFR (0.43) | EGFRGABRA1GABRB2TYRLCK | |
| SCHEMBL9742175 | 0.80 | EGFR (0.43) | EGFRGABRA1GABRB2TYRLCK | |
| SCHEMBL9742172 | 0.80 | EGFR (0.43) | EGFRGABRA1GABRB2TYRLCK | |
| SCHEMBL14283741 | 0.80 | EGFR (0.43) | EGFRGABRA1GABRB2TYRLCK | |
| SCHEMBL11126248 | 0.80 | EGFR (0.43) | EGFRGABRA1GABRB2TYRLCK | |
| SCHEMBL11875937 | 0.77 | AKR1B10 (0.49) | EGFRTYRLCKMAPTCYP3A4 | |
| SCHEMBL14283792 | 0.77 | GABRA1 (0.47) | EGFRGABRA1GABRB2TYRLCK | |
| SCHEMBL11125807 | 0.77 | AKR1B10 (0.49) | EGFRTYRLCKMAPTCYP3A4 | |
| SCHEMBL30893166 | 0.75 | GABRA1 (0.70) | EGFRGABRA1GABRB2TYRMAPT | |
| SCHEMBL8578976 | 0.75 | HSPA5 (0.50) | EGFRMAPTCYP3A4ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6986886-B2 | Hair conditioning compositions and their use in hair coloring compositions | THE PROCTER & GAMBLE COMPANY (US) | 2006-01-17 | — | — | US | disclosed |
| US-20040158941-A1 | Hair colouring and conditioning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2004-08-19 | — | — | US | disclosed |
| US-20040158938-A1 | Method for colouring hair | THE PROCTER & GAMBLE COMPANY | 2004-08-19 | — | — | US | disclosed |
| US-6758866-B2 | AQUEOUS SOLUTION OF CHELATE COMPOUND, OXIDATION COLOR DYE AND COUPLER | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-07-06 | — | — | US | disclosed |
| US-6695888-B2 | COMPLEX TRANSITION METAL HAIR DYE | UNILEVER HOME & PERSONAL CARE, USA, DIVISION OF CONOPCO, INC. | 2004-02-24 | — | — | US | disclosed |
| WO-2004014328-A1 | ONE STEP HAIR COLORING COMPOSITIONS COMPRISING WATER SOLUBLE CARBONATE RELEASING SALTS | UNILEVER PLC (GB) | 2004-02-19 | — | — | WO | disclosed |
| US-20040019980-A1 | One step hair coloring compositions using salts | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-02-05 | — | — | US | disclosed |
| US-20030219399-A1 | Hair conditioning compositions and their use in hair colouring compositions | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-27 | — | — | US | disclosed |
| EP-1341502-A2 | HAIR CONDITIONING COMPOSITIONS AND THEIR USE IN HAIR COLOURING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| EP-0876134-B1 | HAIR COLORING COMPOSITIONS | PROCTER & GAMBLE (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-1998027943-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027945-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027944-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027942-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1998027941-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-07-02 | — | — | WO | disclosed |
| WO-1997024107-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |
| WO-1997024106-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |
| WO-1997024108-A1 | HAIR BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |
| WO-1997024105-A1 | HAIR COLORING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-10 | — | — | WO | disclosed |
| US-3957424-A | Enzyme-activated oxidative process for coloring hair | THE PROCTER & GAMBLE COMPANY (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030219399-A1 | Hair conditioning compositions and their use in hair colouring compositions | CD99, HLA-C, PLOD1 | EGFR 374/4885GABRA1 2222/4885GABRB2 2634/4885 |
| US-20040158941-A1 | Hair colouring and conditioning compositions | FNIP1, CUTA, SHH | EGFR 2246/4885GABRA1 2951/4885GABRB2 3306/4885 |
| US-20040158938-A1 | Method for colouring hair | COX5B, SHH, DNMT3A | EGFR 1257/4885GABRA1 4290/4885GABRB2 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.