Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742742 | 1.00 | HRH3 (0.44) | HRH3RAB9AS1PR3LMNACYP2C9 | |
| SCHEMBL9742301 | 1.00 | HRH3 (0.44) | HRH3RAB9AS1PR3LMNACYP2C9 | |
| SCHEMBL9743946 | 0.99 | RAB9A (0.45) | HRH3RAB9AS1PR3LMNACYP2C9 | |
| SCHEMBL9743953 | 0.99 | RAB9A (0.45) | HRH3RAB9AS1PR3LMNACYP2C9 | |
| SCHEMBL13401992 | 0.92 | RAB9A (0.50) | HRH3RAB9AS1PR3LMNACYP2C9 | |
| SCHEMBL9512268 | 0.91 | RAB9A (0.51) | HRH3RAB9AS1PR3LMNACYP2C9 | |
| SCHEMBL9744280 | 0.90 | S1PR3 (0.41) | HRH3RAB9AS1PR3LMNACYP2C9 | |
| SCHEMBL9743427 | 0.90 | S1PR3 (0.41) | HRH3RAB9AS1PR3LMNACYP2C9 | |
| SCHEMBL9744270 | 0.90 | S1PR3 (0.41) | HRH3RAB9AS1PR3LMNACYP2C9 | |
| SCHEMBL9743422 | 0.90 | S1PR3 (0.41) | HRH3RAB9AS1PR3LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |