Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | PRKX | P51817 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825365 | 1.00 | ALDH1A1 (0.51) | ALDH1A1TRPA1HTR2AHRH1PRKACA | |
| SCHEMBL8722488 | 1.00 | ALDH1A1 (0.51) | ALDH1A1TRPA1HTR2AHRH1PRKACA | |
| Hydrochloric Acid SCHEMBL11398988 | 0.98 | ALDH1A1 (0.50) | ALDH1A1TRPA1HTR2AHRH1PRKACA | |
| SCHEMBL1964722 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TRPA1HTR2AHRH1PRKACA | |
| SCHEMBL1964723 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TRPA1HTR2AHRH1PRKACA | |
| SCHEMBL4110424 | 0.83 | ALDH1A1 (0.55) | ALDH1A1TRPA1HTR2AHRH1PRKACA | |
| SCHEMBL15787637 | 0.82 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15787291 | 0.82 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL172587 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HTR2AHRH1CHRM2ADRA1A | |
| SCHEMBL17864360 | 0.81 | PRKACA (0.49) | ALDH1A1TRPA1HTR2AHRH1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110194719-A | A kind of preparation method in R- (-)-levels Moses spit of fland | 山东大学 | 2019-09-03 | — | — | CN | disclosed |
| CN-107630049-B | The biological preparation method of ephedrine | 武汉茵茂特生物技术有限公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-107630049-B | The biological preparation method of ephedrine | 武汉茵茂特生物技术有限公司 | 2018-09-21 | — | — | CN | disclosed |
| CN-107630050-A | The biological preparation method of pseudoephedrine | 武汉茵茂特生物技术有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107630049-A | The biological preparation method of ephedrine | 武汉茵茂特生物技术有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107630049-A | The biological preparation method of ephedrine | 武汉茵茂特生物技术有限公司 | 2018-01-26 | — | — | CN | disclosed |
| EP-3016951-B1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |
| US-20160152628-A1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-06-02 | — | — | US | disclosed |
| EP-2170848-B1 | PYRAZINONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF LUNG DISEASES | ASTRAZENECA AB (SE) | 2014-10-22 | — | — | EP | disclosed |
| WO-2014159251-A2 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2014-10-02 | — | — | WO | disclosed |
| EP-1165570-B9 | NOVEL PHOSPHORUS-CONTAINING PRODRUGS | METABASIS THERAPEUTICS INC (US) | 2007-02-21 | — | — | EP | disclosed |
| EP-1724276-A1 | Novel phosphorus-containing prodrugs | Metabasis Therapeutics, Inc. (US) | 2006-11-22 | — | — | EP | disclosed |
| EP-1165570-B1 | NOVEL PHOSPHORUS-CONTAINING PRODRUGS | METABASIS THERAPEUTICS INC (US) | 2006-08-23 | — | — | EP | disclosed |
| EP-1634886-A2 | Novel phosphorus-containing prodrug | Metabasis Therapeutics, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| CN-1733779-A | Novel phosphorus-containing prodrug | METABASIS THERAPEUTICS INC (US) | 2006-02-15 | — | — | CN | disclosed |
| WO-2005058892-A1 | PYRAZOLO [3,4-B] PYRIDINE COMPOUNDS, AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-06-30 | — | — | WO | disclosed |
| EP-1379492-A1 | INHIBITOR OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002070457-A1 | INHIBITOR OF MONOAMINE UPTAKE | ELI LILLY AND COMPANY (US) | 2002-09-12 | — | — | WO | disclosed |
| US-5149821-A | Process and intermediates for optically active 3-formyltetrahydropyrans | PFIZER INC (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0391070-A1 | Process for the preparation of N-methyl-3-(p-trifluoro-methylphenoxy)-3-phenyl-propylamine and their salts | ORION-YHTYMÄ OY FERMION (FI) | 1990-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152628-A1 | TRICYCLIC PYRIDO-CARBOXAMIDE DERIVATIVES AS ROCK INHIBITORS | MYLK, MYLK2, ROCK1 | ALDH1A1 3223/4885TRPA1 1445/4885HTR2A 1642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.