Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.40 |
| ▸ | IAPP | P10997 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742648 | 1.00 | TTR (0.45) | TTRSLC37A4IAPPCA2CA1 | |
| SCHEMBL21010269 | 0.88 | TRPA1 (0.43) | TTRSLC37A4IAPPCA2CA1 | |
| SCHEMBL11065635 | 0.88 | TRPA1 (0.43) | TTRSLC37A4IAPPCA2CA1 | |
| SCHEMBL10584572 | 0.83 | TTR (0.42) | TTRSLC37A4IAPPCA2CA1 | |
| SCHEMBL11091395 | 0.79 | IAPP (0.45) | TTRSLC37A4IAPPCA2CA1 | |
| SCHEMBL9744278 | 0.77 | CYP3A4 (0.39) | TTRSLC37A4HPGDTDP1CYP3A4 | |
| SCHEMBL9744284 | 0.77 | CYP3A4 (0.39) | TTRSLC37A4HPGDTDP1CYP3A4 | |
| SCHEMBL29991253 | 0.77 | ESR1 (0.38) | SLC37A4TYMP | |
| SCHEMBL9744084 | 0.77 | IAPP (0.59) | IAPPCA2CA1ALDH1A1EGFR | |
| SCHEMBL9744078 | 0.77 | IAPP (0.59) | IAPPCA2CA1ALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |