Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744278 | 1.00 | CYP3A4 (0.39) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| SCHEMBL9742653 | 0.77 | TTR (0.45) | CYP3A4MEN1KMT2ATTRTDP1 | |
| SCHEMBL9742648 | 0.77 | TTR (0.45) | CYP3A4MEN1KMT2ATTRTDP1 | |
| SCHEMBL1822107 | 0.77 | TTR (0.52) | CYP3A4MEN1KMT2APTGS1TTR | |
| SCHEMBL1822108 | 0.77 | TTR (0.52) | CYP3A4MEN1KMT2APTGS1TTR | |
| SCHEMBL28890060 | 0.74 | LCK (0.59) | CYP3A4MEN1KMT2APTGS1TTR | |
| SCHEMBL9245161 | 0.74 | FASN (0.39) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| SCHEMBL28266636 | 0.74 | PTPN1 (0.42) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| SCHEMBL9742118 | 0.73 | CNR2 (0.41) | CYP3A4MEN1KMT2APTGS1DRD3 | |
| SCHEMBL9742123 | 0.73 | CNR2 (0.41) | CYP3A4MEN1KMT2APTGS1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |