Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 7/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640697 | 0.83 | DRD3 (0.35) | CNR2DRD3 | |
| Hydrochloric Acid SCHEMBL9651222 | 0.82 | DRD3 (0.35) | CNR2DRD3 | |
| SCHEMBL9742165 | 0.81 | PIK3CA (0.35) | DRD3PIK3CAPIK3CB | |
| SCHEMBL9868201 | 0.78 | DRD3 (0.49) | DRD3 | |
| SCHEMBL2298189 | 0.73 | PDE10A (0.42) | CNR2DRD3PDE10A | |
| SCHEMBL2293475 | 0.73 | PDE10A (0.42) | CNR2DRD3PDE10A | |
| SCHEMBL9640630 | 0.71 | DRD3 (0.44) | CNR2DRD3 | |
| Hydrochloric Acid SCHEMBL9640898 | 0.70 | DRD3 (0.43) | CNR2DRD3 | |
| SCHEMBL12363949 | 0.69 | CNR2 (0.45) | CNR2DRD3 | |
| SCHEMBL9641992 | 0.69 | CNR2 (0.45) | CNR2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077290-A | Animal growth regulators, bronchodilators, antidepressants and antiobesity agents | MERCK & CO., INC. (US) | 1991-12-31 | — | — | US | claimed |
| US-5124328-A | Animal growth antidepressants regulators | MERCK & CO., INC. (US) | 1992-06-23 | — | — | US | disclosed |
| US-5077290-A | Animal growth regulators, bronchodilators, antidepressants and antiobesity agents | MERCK & CO., INC. (US) | 1991-12-31 | — | — | US | disclosed |