Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742987 | 1.00 | MAPT (0.49) | MAPTKDM4EALDH1A1MEN1RECQL | |
| SCHEMBL9744309 | 0.84 | IDH1 (0.52) | MAPTKDM4EALDH1A1MEN1RECQL | |
| SCHEMBL9744306 | 0.84 | IDH1 (0.52) | MAPTKDM4EALDH1A1MEN1RECQL | |
| SCHEMBL454263 | 0.83 | KDM4E (0.46) | MAPTKDM4EALDH1A1MEN1RECQL | |
| SCHEMBL11781698 | 0.82 | PTGS1 (0.62) | MAPTKDM4EALDH1A1MEN1RECQL | |
| SCHEMBL11781704 | 0.82 | PTGS1 (0.62) | MAPTKDM4EALDH1A1MEN1RECQL | |
| SCHEMBL28361770 | 0.81 | KDM4E (0.45) | MAPTKDM4EALDH1A1MEN1RECQL | |
| SCHEMBL31545794 | 0.79 | PPARG (0.58) | MAPTKDM4EALDH1A1MEN1RECQL | |
| Pinosylvin SCHEMBL2237660 | 0.79 | LCK (0.52) | MAPTKDM4EALDH1A1MEN1RECQL | |
| SCHEMBL2467754 | 0.79 | MAPT (0.53) | MAPTKDM4EALDH1A1MEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |