Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743920 | 0.87 | TMEM97 (0.44) | USP2GAAACHE | |
| SCHEMBL9743459 | 0.86 | ABL1 (0.39) | RAB9AUSP2GAAALDH1A1MAPT | |
| SCHEMBL9743960 | 0.83 | ALDH1A1 (0.56) | SMN1; SMN2GAAALDH1A1MAPTKDM4E | |
| SCHEMBL9743934 | 0.81 | CLK1 (0.52) | RAB9ANPC1SMN1; SMN2USP2GAA | |
| SCHEMBL9743503 | 0.75 | TMEM97 (0.57) | RAB9ANPC1SMN1; SMN2HRH3 | |
| SCHEMBL9742816 | 0.74 | TMEM97 (0.50) | RAB9ANPC1SMN1; SMN2USP2GAA | |
| SCHEMBL9744020 | 0.74 | HSP90AA1 (0.46) | USP2GAAALDH1A1MAPTKDM4E | |
| SCHEMBL9743877 | 0.74 | CASR (0.45) | RAB9ANPC1SMN1; SMN2USP2GAA | |
| SCHEMBL9214629 | 0.74 | GAA (0.40) | RAB9ANPC1USP2GAAALDH1A1 | |
| SCHEMBL9182499 | 0.72 | DYRK1A (0.39) | ILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |