Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.57 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743920 | 0.88 | TMEM97 (0.44) | TMEM97DRD3DRD2HTR1AHTR2A | |
| SCHEMBL9439734 | 0.79 | LOXL2 (0.47) | LOXL2NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9743348 | 0.79 | KCNH2 (0.43) | TMEM97DRD3DRD2HTR1AHTR2A | |
| SCHEMBL9743934 | 0.79 | CLK1 (0.52) | DRD3DRD2DRD4NPC1RAB9A | |
| SCHEMBL24233783 | 0.76 | TMEM97 (0.59) | TMEM97DRD3DRD2HTR1AHTR2A | |
| SCHEMBL30470853 | 0.76 | TMEM97 (0.59) | TMEM97DRD3DRD2HTR1AHTR2A | |
| SCHEMBL9439615 | 0.74 | SMN1; SMN2 (0.42) | TMEM97DRD3DRD2HTR1AHTR2A | |
| SCHEMBL9743903 | 0.74 | TMEM97 (0.86) | TMEM97SMN1; SMN2 | |
| SCHEMBL9744944 | 0.74 | LOXL2 (0.42) | TMEM97LOXL2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6475090 | 0.74 | SMN1; SMN2 (0.42) | LOXL2NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |