Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743171 | 1.00 | CYP2C9 (0.43) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9745741 | 0.93 | SPHK1 (0.42) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9745733 | 0.93 | SPHK1 (0.42) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9743390 | 0.93 | SPHK1 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9743383 | 0.93 | SPHK1 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9743880 | 0.92 | SPHK1 (0.47) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9743888 | 0.92 | SPHK1 (0.47) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9742951 | 0.92 | SPHK1 (0.41) | CYP2C9ASIC3BCHESPHK1 | |
| SCHEMBL9742946 | 0.92 | SPHK1 (0.41) | CYP2C9ASIC3BCHESPHK1 | |
| SCHEMBL9743077 | 0.91 | ASIC3 (0.39) | CYP2C9ASIC3SPHK1ACACBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084204-A | Naphthylacetylenes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-01-28 | — | — | US | disclosed |