Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762440 | 0.89 | GABRA1 (0.55) | APPCA1CA2CA12CA9 | |
| SCHEMBL28003619 | 0.87 | CA1 (0.50) | APPCA1CA2CA12CA9 | |
| SCHEMBL8346295 | 0.86 | TLR8 (0.49) | APPCA1CA2CA12CA9 | |
| SCHEMBL22453135 | 0.84 | ESR2 (0.53) | APPCA1CA2CA12CA9 | |
| SCHEMBL8817638 | 0.84 | CA1 (0.51) | APPCA1CA2CA12CA9 | |
| SCHEMBL9742690 | 0.83 | GABRA1 (0.52) | APPCA1CA2CA12CA9 | |
| SCHEMBL4241557 | 0.79 | APP (0.50) | APPTRPA1ALOX5LMNASLC6A2 | |
| SCHEMBL1513629 | 0.79 | CA1 (0.56) | CA1CA2CA12CA9GABRA1 | |
| SCHEMBL11833116 | 0.78 | CA12 (0.46) | APPCA1CA2CA12CA9 | |
| SCHEMBL30865718 | 0.78 | TRPA1 (0.51) | CA1CA2CA12CA9GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |