Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891230 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL31585050 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL6996539 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL8044989 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL8035702 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL11375095 | 0.74 | CYP3A4 (0.39) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL9734250 | 0.74 | CCR1 (0.54) | SMN1; SMN2ALDH1A1CCR1CYP4F2CYP4A11 | |
| SCHEMBL29547761 | 0.73 | MAPT (0.45) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL9735256 | 0.72 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL3134099 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2MEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164386-A | Gastrointestinal and respiratory disorders | ISTITUTO DE ANGELI S.P.A. (IT) | 1992-11-17 | — | — | US | disclosed |