Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701485 | 0.77 | ALDH1A1 (0.41) | L3MBTL1CYP3A4TSHRKMT2ACYP2D6 | |
| SCHEMBL7828236 | 0.76 | L3MBTL1 (0.47) | SMN1; SMN2L3MBTL1BLMSLC22A2SLC22A1 | |
| SCHEMBL6775828 | 0.75 | PLCG1 (0.37) | SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL25500507 | 0.74 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1BLMSLC22A2SLC22A1 | |
| SCHEMBL3743980 | 0.74 | L3MBTL1 (0.46) | SMN1; SMN2L3MBTL1BLMSLC22A2SLC22A1 | |
| SCHEMBL15693459 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1BLMGAASLC22A2 | |
| SCHEMBL21246245 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1BLMGAASLC22A2 | |
| SCHEMBL13269728 | 0.73 | L3MBTL1 (0.44) | SMN1; SMN2L3MBTL1BLMSLC22A2SLC22A1 | |
| SCHEMBL9743183 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2L3MBTL1GAATDP1MEN1 | |
| SCHEMBL1151512 | 0.72 | L3MBTL1 (0.37) | SMN1; SMN2L3MBTL1GAATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164386-A | Gastrointestinal and respiratory disorders | ISTITUTO DE ANGELI S.P.A. (IT) | 1992-11-17 | — | — | US | disclosed |
| EP-0270830-A1 | Method for regulating plant growth using polysubstituted butyric acids, esters and derivatives thereof | AMERICAN CYANAMID COMPANY (US) | 1988-06-15 | — | — | EP | disclosed |