SCHEMBL9743231

SCHEMBL9743231

Oc1ccc(CC=Cc2ccccc2)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.54
ALDH1A1 P00352 3/20 0.54
MAPT P10636 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CYP3A4 P08684 2/20 0.54
ALOX15 P16050 2/20 0.54
RECQL P46063 1/20 0.54
TP53 P04637 1/20 0.54
ALOX5 P09917 2/20 0.51
THRB P10828 1/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
TYR P14679 1/20 0.47
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46
PTGER2 P43116 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9743227 1.00 KDM4E (0.54) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL30555743 1.00 KDM4E (0.54) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL11795502 0.92 ALOX5 (0.49) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL11795492 0.92 ALOX5 (0.49) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL9743207 0.86 KDM4E (0.54) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL31233060 0.86 KDM4E (0.54) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL9743212 0.86 KDM4E (0.54) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL24075548 0.85 KDM4E (0.52) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL25113201 0.83 KDM4E (0.51) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL24075726 0.83 ALDH1A1 (0.51) KDM4EALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3951820-A Mixture of cinnamylphenols and normally spoilable substance THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-04-20 US claimed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed
US-3951820-A Mixture of cinnamylphenols and normally spoilable substance THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-04-20 US disclosed
US-3936393-A 2-METHOXY-4-CINNAMYL PHENOL THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-02-03 US disclosed