Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644469 | 0.91 | ALDH1A1 (0.38) | ACE2ALDH1A1CA12CA9KDM4E | |
| SCHEMBL10894132 | 0.90 | ALDH1A1 (0.43) | ACE2ALDH1A1CA12CA9KDM4E | |
| SCHEMBL7644691 | 0.88 | ALDH1A1 (0.45) | ACE2ALDH1A1CA12CA9SLC37A4 | |
| SCHEMBL6447198 | 0.88 | ACE2 (0.38) | ACE2ALDH1A1CA12CA9KDM4E | |
| SCHEMBL8603134 | 0.85 | ACE2 (0.40) | ACE2ALDH1A1CA12CA9KDM4E | |
| SCHEMBL5515097 | 0.84 | ALDH1A1 (0.44) | ACE2ALDH1A1CA12CA9SLC37A4 | |
| SCHEMBL5525340 | 0.81 | ALDH1A1 (0.44) | ACE2ALDH1A1CA12CA9SLC37A4 | |
| SCHEMBL6444436 | 0.81 | KDM4E (0.40) | ACE2ALDH1A1CA12CA9KDM4E | |
| SCHEMBL7649720 | 0.79 | SLC37A4 (0.43) | ALDH1A1CA12CA9KDM4EMEN1 | |
| SCHEMBL11616577 | 0.78 | ALDH1A1 (0.34) | ACE2ALDH1A1CA12CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089460-A | Coordination catalyst | ACADEMY OF APPLIED SCIENCE, INC. (US) | 1992-02-18 | — | — | US | claimed |
| US-5089460-A | Coordination catalyst | ACADEMY OF APPLIED SCIENCE, INC. (US) | 1992-02-18 | — | — | US | disclosed |