SCHEMBL974341

SCHEMBL974341

C/C(=C\C(=O)OCCCCCCCCC(=O)O)C[C@@H]1OC[C@H](C/C=C/[C@@H](C)[C@H](C)O)[C@@H](O)[C@H]1O

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IARS1 P41252 5/20 0.69
HTR2A P28223 1/20 0.69
PTGFR P43088 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14616862 1.00 IARS1 (0.69) IARS1HTR2APTGFR
SCHEMBL14045603 0.87 IARS1 (0.66) IARS1HTR2A
SCHEMBL29885016 0.84 IARS1 (0.51) IARS1HTR2A
SCHEMBL29885136 0.84 IARS1 (0.51) IARS1HTR2A
SCHEMBL19183608 0.82 IARS1 (0.69) IARS1HTR2A
SCHEMBL9033558 0.82 HTR2A (0.44) IARS1HTR2A
Mupirocin SCHEMBL15387504 0.82 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL18995884 0.82 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL1027616 0.82 IARS1 (1.00) IARS1HTR2A
Mupirocin SCHEMBL3291 0.82 IARS1 (1.00) IARS1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110015413-A1 PROCESS FOR PREPARING CRYSTALLINE CALCIUM MUPIROCIN DIHYDRATE DEFTERDAROVIC NAFIS 2011-01-20 US claimed
WO-2009092991-A1 PROCESS FOR PREPARING CRYSTALLINE CALCIUM MUPIROCIN DIHYDRATE PLIVA HRVATSKA D.O.O. (HR) 2009-07-30 WO claimed
CN-1126493-A Enzymatic preparation of monic acids SMITHKLINE BEECHAM PLC (GB) 1996-07-10 CN claimed
EP-0707657-A1 ENZYMATIC PREPARATION OF MONIC ACIDS SMITHKLINE BEECHAM PLC (GB) 1996-04-24 EP claimed
WO-1995002064-A1 ENZYMATIC PREPARATION OF MONIC ACIDS SMITHKLINE BEECHAM PLC (GB) 1995-01-19 WO claimed
EP-0003069-B1 PSEUDOMONIC ACID C, PHARMACEUTICALLY ACCEPTABLE SALTS OR ESTERS THEREOF, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL OR VETERINARY COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1981-05-20 EP claimed
US-4226880-A PSEUDOMONIC ACID C AND DERIVATIVES BEECHAM GROUP LIMITED (GB) 1980-10-07 US claimed
US-4205002-A PSEUDOMONIC ACID C AND DERIVATIVES BEECHAM GROUP LIMITED (GB) 1980-05-27 US claimed
EP-0003069-A1 Pseudomonic acid C, pharmaceutically acceptable salts or esters thereof, processes for their preparation and pharmaceutical or veterinary compositions containing them BEECHAM GROUP PLC (GB) 1979-07-25 EP claimed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
CN-108277243-B Preparation method of pseudomonic acid A 浙江瑞邦药业股份有限公司 2021-03-12 CN disclosed
CN-111220721-A Mupirocin ointment impurity qualitative positioning and testing method and application 湖北人福成田药业有限公司 2020-06-02 CN disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-4205002-A PSEUDOMONIC ACID C AND DERIVATIVES BEECHAM GROUP LIMITED (GB) 1980-05-27 US disclosed
EP-0005006-A2 Antibacterial monic acid C derivatives, processes for their preparation and compositions containing them BEECHAM GROUP PLC (GB) 1979-10-31 EP disclosed
EP-0005006-A2 Antibacterial monic acid C derivatives, processes for their preparation and compositions containing them BEECHAM GROUP PLC (GB) 1979-10-31 EP disclosed
EP-0003069-A1 Pseudomonic acid C, pharmaceutically acceptable salts or esters thereof, processes for their preparation and pharmaceutical or veterinary compositions containing them BEECHAM GROUP PLC (GB) 1979-07-25 EP disclosed
EP-0003069-A1 Pseudomonic acid C, pharmaceutically acceptable salts or esters thereof, processes for their preparation and pharmaceutical or veterinary compositions containing them BEECHAM GROUP PLC (GB) 1979-07-25 EP disclosed
EP-0003069-A1 Pseudomonic acid C, pharmaceutically acceptable salts or esters thereof, processes for their preparation and pharmaceutical or veterinary compositions containing them BEECHAM GROUP PLC (GB) 1979-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015413-A1 PROCESS FOR PREPARING CRYSTALLINE CALCIUM MUPIROCIN DIHYDRATE CACYBP, CAPRIN1, PRCP IARS1 4569/4885HTR2A 3039/4885PTGFR 4743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.