Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IARS1 | P41252 | 5/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | PTGFR | P43088 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974341 | 1.00 | IARS1 (0.69) | IARS1HTR2APTGFR | |
| SCHEMBL14045603 | 0.87 | IARS1 (0.66) | IARS1HTR2A | |
| SCHEMBL29885016 | 0.84 | IARS1 (0.51) | IARS1HTR2A | |
| SCHEMBL29885136 | 0.84 | IARS1 (0.51) | IARS1HTR2A | |
| SCHEMBL19183608 | 0.82 | IARS1 (0.69) | IARS1HTR2A | |
| SCHEMBL9033558 | 0.82 | HTR2A (0.44) | IARS1HTR2A | |
| Mupirocin SCHEMBL15387504 | 0.82 | IARS1 (1.00) | IARS1HTR2A | |
| Mupirocin SCHEMBL18995884 | 0.82 | IARS1 (1.00) | IARS1HTR2A | |
| Mupirocin SCHEMBL1027616 | 0.82 | IARS1 (1.00) | IARS1HTR2A | |
| Mupirocin SCHEMBL3291 | 0.82 | IARS1 (1.00) | IARS1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018023-A1 | COMPOSITIONS FOR TOPICAL ADMINISTRATION | SOL-GEL TECHNOLOGIES LTD. (IL) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018023-A1 | COMPOSITIONS FOR TOPICAL ADMINISTRATION | RDX, PRXL2A, PRDX1 | IARS1 2874/4885HTR2A 4785/4885PTGFR 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.