SCHEMBL9743508

SCHEMBL9743508

O=S(=O)(O)CNc1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
HPGD P15428 3/20 0.52
ALOX15 P16050 3/20 0.52
CASP1 P29466 3/20 0.52
HSD17B10 Q99714 3/20 0.52
THRB P10828 2/20 0.52
CYP3A4 P08684 2/20 0.52
HIF1A Q16665 2/20 0.52
TP53 P04637 1/20 0.52
RECQL P46063 1/20 0.52
CA2 P00918 6/20 0.47
CA1 P00915 5/20 0.47
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 3/20 0.41
MEN1 O00255 3/20 0.41
MAPT P10636 3/20 0.41
KMT2A Q03164 3/20 0.41
POLB P06746 2/20 0.41
GAA P10253 2/20 0.41
MAPK1 P28482 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11311089 0.91 CA2 (0.45) ALDH1A1HPGDALOX15CASP1HSD17B10
SCHEMBL5175495 0.81 MAPT (0.52) ALDH1A1HPGDALOX15CASP1HSD17B10
SCHEMBL1485834 0.81 CA2 (0.38) ALDH1A1HPGDALOX15CASP1HSD17B10
SCHEMBL1485836 0.81 TSHR (0.45) ALDH1A1CYP3A4CA2CA1LMNA
SCHEMBL1956114 0.80 CA2 (0.61) ALDH1A1CYP3A4TP53CA2CA1
Sulfuric Acid SCHEMBL9450963 0.78 ALDH1A1 (0.57) ALDH1A1HPGDALOX15CASP1HSD17B10
SCHEMBL2183092 0.78 CA2 (0.59) ALDH1A1CYP3A4TP53CA2CA1
Mesulfamide SCHEMBL2110450 0.78 CA2 (0.58) CA2CA1MEN1KMT2ACA12
Sulfuric Acid SCHEMBL9257267 0.77 ALDH1A1 (0.61) ALDH1A1HPGDALOX15CASP1HSD17B10
SCHEMBL3395150 0.77 CA2 (0.38) CA2CA1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120855-A Formation of hydroxyaromatic ketoacetal from a hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and Dp-hydroxyphenylglycine from 4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1992-06-09 US claimed
JP-52093741-A None JP disclosed
US-20240076315-A1 KHL POLYPEPTIDE, AND USE THEREOF IN PREPARATION OF TABP-EIC CELL ALLIFE MEDICINE (ZHUHAI) LIMITED (CN) 2024-03-07 US disclosed
CN-110612447-B Assays for detecting early pancreatic cancer 德克萨斯州立大学董事会 2024-02-06 CN disclosed
CN-113403385-B Use of MEF2C in the diagnosis and treatment of asthma 江苏大学附属医院 2022-06-24 CN disclosed
CN-113402590-B KHL polypeptide and application thereof in preparation of TABP-EIC cells 呈诺再生医学科技(珠海横琴新区)有限公司 2022-05-10 CN disclosed
CN-114217063-A Application of FBLN1 and CTSF combination in diagnosis of non-small cell lung cancer brain metastasis 大连医科大学附属第二医院 2022-03-22 CN disclosed
CN-113930508-A Marker for predicting sensitivity of rectal cancer patient to bevacizumab 青岛泱深生物医药有限公司 2022-01-14 CN disclosed
CN-113832149-A Prediction marker of bevacizumab sensitivity and application thereof 青岛泱深生物医药有限公司 2021-12-24 CN disclosed
CN-113832229-A Use of biomarkers for predicting bevacizumab sensitivity 青岛泱深生物医药有限公司 2021-12-24 CN disclosed
CN-113164547-A Nucleic acids for cell recognition and integration 爱默蕾大学 2021-07-23 CN disclosed
US-20120034565-A1 Lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-02-09 US disclosed
US-5120855-A Formation of hydroxyaromatic ketoacetal from a hydroxyaromatic methylketone and production of 5-(4'-hydroxyphenyl)hydantoin and Dp-hydroxyphenylglycine from 4-hydroxyacetophenone HOECHST CELANESE CORPORATION (US) 1992-06-09 US disclosed
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4188212-A BEZNOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JP) 1980-02-12 US disclosed
JP-S5293741-A P-HYDROXYPHENYLGLYCINE-SULFONIC ACID DERIVATIVE SALTS NIPPON KAYAKU CO LTD 1977-08-06 JP disclosed
US-3994962-A INTERMEDIATE FOR PENICILLIN AND CEPHALOSPORIN DERIVATIVES NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1976-11-30 US disclosed
US-3994962-A INTERMEDIATE FOR PENICILLIN AND CEPHALOSPORIN DERIVATIVES NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1976-11-30 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed