Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.90 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.90 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.90 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.90 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.90 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.90 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.90 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.90 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743556 | 1.00 | TACR1 (0.90) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| Cp-96345 SCHEMBL1447963 | 0.95 | TACR1 (1.00) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| Cp-96345 SCHEMBL675160 | 0.95 | TACR1 (1.00) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| Cp-96345 SCHEMBL5673687 | 0.95 | TACR1 (1.00) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| Cp-96345 SCHEMBL5419350 | 0.95 | TACR1 (1.00) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| Cp-96345 SCHEMBL675159 | 0.95 | TACR1 (1.00) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| Cp-96345 SCHEMBL5378537 | 0.95 | TACR1 (1.00) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| Cp-96345 SCHEMBL5419344 | 0.95 | TACR1 (1.00) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| Cp-96345 SCHEMBL29386897 | 0.95 | TACR1 (1.00) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| Cp-96345 SCHEMBL5419354 | 0.95 | TACR1 (1.00) | TACR1CACNA1FCHRM5CACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162339-A | Substance P Antagonists, Gastrointestinal and Central Nervous System Disorders, Antiinflammatory Agents, Analgesics | PFIZER INC. (US) | 1992-11-10 | — | — | US | disclosed |