Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742473 | 0.86 | HTT (0.67) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL918394 | 0.82 | PPARG (0.51) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6469802 | 0.82 | PPARG (0.51) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9745445 | 0.80 | CA9 (0.39) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6832976 | 0.80 | HTT (0.52) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL1179405 | 0.78 | HTT (0.68) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL9743217 | 0.78 | HTT (0.56) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6450486 | 0.77 | PPARG (0.41) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6450483 | 0.77 | PPARG (0.41) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL6311612 | 0.77 | PPARG (0.41) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |