SCHEMBL6832976

SCHEMBL6832976

CCCc1c(O)cc(O)cc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.52
NPC1 O15118 1/20 0.52
HPGD P15428 1/20 0.52
MAPK1 P28482 1/20 0.52
RAB9A P51151 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
PTPN1 P18031 1/20 0.48
PTPN11 Q06124 1/20 0.48
SLC28A3 Q9HAS3 1/20 0.48
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
PGAM1 P18669 1/20 0.45
TYR P14679 2/20 0.43
CYP3A4 P08684 3/20 0.43
PTGS2 P35354 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
PTGS1 P23219 1/20 0.43
DRD3 P35462 1/20 0.43
TDP1 Q9NUW8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1179417 0.86 PTPN1 (0.56) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL70738 0.86 NPC1 (0.45) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL9743295 0.85 HTT (0.72) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL168062 0.83 HTT (0.63) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL16046757 0.83 SLC28A3 (0.56) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL1179405 0.82 HTT (0.68) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL9743217 0.82 HTT (0.56) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL19433098 0.81 PTGS2 (0.61) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL19433103 0.81 PTGS2 (0.61) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL19433099 0.81 PTGS2 (0.61) HTTNPC1HPGDMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 US disclosed
US-11045402-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-06-29 US disclosed
US-10959925-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-03-30 US disclosed
EP-3228302-B1 HAIR DEFORMATION TREATMENT AGENT KAO CORP (JP) 2020-09-02 EP disclosed
CN-106999382-B Hair deforming agent 花王株式会社 2020-07-10 CN disclosed
US-20200199058-A1 SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES NITTO DENKO CORPORATION (JP) 2020-06-25 US disclosed
US-20190290564-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-09-26 US disclosed
US-20190254943-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-08-22 US disclosed
US-20190224093-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-07-25 US disclosed
US-20190125052-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-05-02 US disclosed
EP-3228300-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 EP disclosed
EP-3228302-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 EP disclosed
CN-106999382-A Hair deformation process agent 花王株式会社 2017-08-01 CN disclosed
US-9567433-B2 Methods for forming a polycarbonate with a hydrophilic surface GM Global Technology Operations LLC (US) 2017-02-14 US disclosed
US-20160264729-A1 METHODS FOR FORMING A POLYCARBONATE WITH A HYDROPHILIC SURFACE GM GLOBAL TECHNOLOGY OPERATIONS LLC. 2016-09-15 US disclosed
US-6746629-B2 SCREENING NEON EMISSIONS MITSUBISHI CHEMICAL CORPORATION (JP) 2004-06-08 US disclosed
US-20020014819-A1 Squarylium compounds, filters for plasma display panels employing them, and plasma display panel devices MITSUBISHI CHEMICAL CORPORATION (JP) 2002-02-07 US disclosed
EP-1160230-A1 SQUARYLIUM COMPOUNDS, FILTERS FOR PLASMA DISPLAY PANELS MADE BY USING THE SAME, AND PLASMA DISPLAY PANELS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-12-05 EP disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020014819-A1 Squarylium compounds, filters for plasma display panels employing them, and plasma display panel devices IGSF11, F2, IGLV6-57 HTT 4754/4885NPC1 1702/4885HPGD 4416/4885
US-11045402-B2 Hair cosmetic composition CUTA, GRHPR, POLR1C HTT 46/4885NPC1 3393/4885HPGD 921/4885
US-10959925-B2 Hair cosmetic composition CUTA, POLR1C, GRHPR HTT 137/4885NPC1 2350/4885HPGD 956/4885
US-20190254943-A1 HAIR COSMETIC COMPOSITION CUTA, POLR1C, GRHPR HTT 137/4885NPC1 2350/4885HPGD 956/4885
US-20190125052-A1 METHOD FOR TREATING HAIR GRHPR, TYR, POLR1C HTT 433/4885NPC1 3376/4885HPGD 530/4885
US-20190224093-A1 HAIR COSMETIC COMPOSITION CUTA, GRHPR, POLR1C HTT 46/4885NPC1 3393/4885HPGD 921/4885
US-20200199058-A1 SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES SQLE, FDFT1, ALDH1A2 HTT 4723/4885NPC1 1717/4885HPGD 1575/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 HTT 208/4885NPC1 2673/4885HPGD 1809/4885
US-20190290564-A1 HAIR COSMETIC COMPOSITION GRHPR, POLR1C, TYR HTT 136/4885NPC1 2487/4885HPGD 548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.