Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744064 | 0.80 | NPC1 (0.48) | CA9CA12CA1CA3CA6 | |
| SCHEMBL544300 | 0.78 | CYP3A4 (0.46) | CA9CA12CA1CA14HTT | |
| SCHEMBL9742473 | 0.77 | HTT (0.67) | MAPTHTTMAPK1KDM4EALOX15 | |
| SCHEMBL1179394 | 0.76 | TRPA1 (0.54) | MAPTHTTMAPK1KDM4EALOX15 | |
| SCHEMBL9579926 | 0.76 | SELL (0.52) | MAPTHTTMAPK1KDM4EALOX15 | |
| SCHEMBL3849718 | 0.75 | CA3 (0.52) | CA9CA3CA6CA5ACA14 | |
| SCHEMBL28401269 | 0.75 | HPGD (0.41) | MAPTHTTMAPK1KDM4EALOX15 | |
| SCHEMBL9742867 | 0.74 | CYP3A4 (0.38) | HTTMAPK1ALOX15LMNANPC1 | |
| SCHEMBL9743242 | 0.74 | ALDH1A1 (0.44) | MAPTHTTMAPK1ALOX15LMNA | |
| SCHEMBL27930403 | 0.74 | NPC1 (0.58) | HTTMAPK1ALOX15HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |