Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722922 | 0.83 | GABRA1 (0.41) | KDM4EATMPOLBCYP1A2CYP2D6 | |
| SCHEMBL14854686 | 0.83 | SMN1; SMN2 (0.51) | KDM4EATMCYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL6382375 | 0.82 | KDM4E (0.52) | KDM4EPOLBTSHRHPGDSMN1; SMN2 | |
| SCHEMBL9722931 | 0.81 | CES2 (0.44) | — | |
| SCHEMBL3810854 | 0.81 | CLCN2 (0.52) | KDM4EALDH1A1HPGDCA1CA2 | |
| SCHEMBL2708451 | 0.81 | SLC6A4 (0.51) | KDM4EATMCYP1A2CYP2D6TSHR | |
| SCHEMBL30301996 | 0.81 | SLC6A4 (0.51) | KDM4EATMCYP1A2CYP2D6TSHR | |
| SCHEMBL9743326 | 0.80 | KDM4E (0.70) | KDM4EPOLBCYP1A2CYP2D6TSHR | |
| SCHEMBL22957967 | 0.80 | KDM4E (0.59) | KDM4EATMPOLBALDH1A1HPGD | |
| SCHEMBL21751026 | 0.80 | KDM4E (0.59) | KDM4EATMPOLBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093364-A | 5-FLUOROANTHRANILIC FUNGICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-03-03 | — | — | US | disclosed |
| EP-0360417-A2 | Derivatives of 4-fluoroanthranilic acid and their use as fungicides | SCHERING AGROCHEMICALS LIMITED (GB) | 1990-03-28 | — | — | EP | disclosed |
| US-4772614-A | QUINOLINOLS | THE BOOTS COMPANY (GB) | 1988-09-20 | — | — | US | disclosed |
| EP-0135367-B1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1988-03-16 | — | — | EP | disclosed |
| CN-86104611-A | The preparation method of therapeutical agent | — | 1988-01-27 | — | — | CN | disclosed |
| US-4659718-A | VASODILATION | THE BOOTS COMPANY PLC (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0206616-A2 | Quinolones having antihypertensive activity | The Boots Company PLC (GB) | 1986-12-30 | — | — | EP | disclosed |
| EP-0135367-A1 | Therapeutic agents | The Boots Company PLC (GB) | 1985-03-27 | — | — | EP | disclosed |