Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745009 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2TRPA1PTGS1CACNA1C | |
| Diethylamine SCHEMBL16100003 | 0.80 | GABRA1 (0.50) | GABRA1GABRB2TRPA1PTGS1CACNA1C | |
| SCHEMBL9743490 | 0.79 | NPC1 (0.62) | GABRA1GABRB2TRPA1PTGS1CACNA1C | |
| SCHEMBL23847810 | 0.77 | GABRA1 (0.36) | GABRA1GABRB2TRPA1PTGS1CACNA1C | |
| SCHEMBL6294990 | 0.76 | GABRA1 (0.61) | GABRA1GABRB2TRPA1PTGS1CACNA1C | |
| SCHEMBL17027173 | 0.74 | GABRA1 (0.44) | GABRA1GABRB2TRPA1PTGS1CACNA1C | |
| SCHEMBL544300 | 0.74 | CYP3A4 (0.46) | TRPA1PTGS1HSP90AB1TYRHTT | |
| SCHEMBL6346880 | 0.74 | GABRA1 (0.73) | GABRA1GABRB2TRPA1PTGS1CACNA1C | |
| SCHEMBL28217295 | 0.73 | GABRA1 (0.46) | GABRA1GABRB2HSP90AB1ALDH1A1CA1 | |
| SCHEMBL24213898 | 0.73 | FABP3 (0.39) | GABRA1GABRB2HSP90AA1HSP90AB1TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |