Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 3/20 | 0.45 |
| ▸ | FABP3 | P05413 | 2/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304547 | 0.85 | GABRA1 (0.44) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL22905736 | 0.80 | LMNA (0.37) | GABRA1GABRG2GABRB3CA1CA2 | |
| SCHEMBL8134393 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL8136838 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL6064666 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL25138922 | 0.78 | GCGR (0.38) | GABRA1GABRG2GABRB3CA1CA2 | |
| SCHEMBL22899687 | 0.78 | GABRA1 (0.54) | GABRA1GABRG2GABRB3CA1CA2 | |
| SCHEMBL25219460 | 0.78 | GABRA1 (0.45) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL22899668 | 0.78 | GABRA1 (0.54) | GABRA1GABRG2GABRB3CA1CA2 | |
| SCHEMBL8127965 | 0.78 | GABRA1 (0.58) | GABRA1GABRB2FABP4FABP3FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103524392-B | As for treating the azetidine of the MEK inhibitor of proliferative disease | 埃克塞利希斯股份有限公司 | 2018-06-01 | — | — | CN | disclosed |