SCHEMBL9744288

SCHEMBL9744288

CCCCc1cc(O)c(CCCC)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 1.00
NPC1 O15118 1/20 1.00
HPGD P15428 1/20 1.00
MAPK1 P28482 1/20 1.00
RAB9A P51151 1/20 1.00
NPSR1 Q6W5P4 1/20 1.00
PTGS2 P35354 3/20 0.54
CYP3A4 P08684 1/20 0.54
KDM4E B2RXH2 1/20 0.52
PKM P14618 1/20 0.52
SLC28A3 Q9HAS3 1/20 0.48
CNR1 P21554 2/20 0.47
CNR2 P34972 2/20 0.47
TRPV1 Q8NER1 2/20 0.47
TRPA1 O75762 1/20 0.47
INHA P05111 1/20 0.47
SLC6A2 P23975 1/20 0.47
HTR2A P28223 1/20 0.47
SLC6A4 P31645 1/20 0.47
OPRM1 P35372 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20477532 0.96 HTT (0.92) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL18782422 0.96 HTT (0.92) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL27930400 0.95 NPC1 (0.91) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL9745513 0.93 HTT (0.88) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL9743684 0.93 NPC1 (0.88) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL27693672 0.93 HTT (0.88) HTTNPC1HPGDMAPK1RAB9A
Resorstatin SCHEMBL17867326 0.91 NPC1 (0.84) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL11187337 0.91 NPC1 (0.84) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL20357485 0.91 NPC1 (0.84) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL31545545 0.91 NPC1 (0.84) HTTNPC1HPGDMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 US disclosed
CN-102936348-B Crylic acid water-absorbent resin with excellent water-retaining property and yellowing resistance and preparation method thereof WANHUA CHEMICAL GROUP CO LTD 2013-12-18 CN disclosed
CN-103415480-A Paste and method for manufacturing panel for flat display TORAY INDUSTRIES 2013-11-27 CN disclosed
CN-102936348-A Crylic acid water-absorbent resin with excellent water-retaining property and yellowing resistance and preparation method thereof YANTAI WANHUA POLYURETHANES CO 2013-02-20 CN disclosed
CN-102757693-A Photocurable ink composition, recording method and apparatus, photocurable ink composition for inkjet recording, and inkjet recording method SEIKO EPSON CORP 2012-10-31 CN disclosed
CN-102471149-A Radiation curable coatings for optical fibers DSM IP ASSETS BV 2012-05-23 CN disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed
US-4129413-A Oxidation hair dyes based upon tetraaminopyrimidine developers and mono- and dialkyl -m- dihydroxy benzene couplers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1978-12-12 US disclosed