Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.84 |
| ▸ | HPGD | P15428 | 1/20 | 0.84 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.84 |
| ▸ | HTT | P42858 | 1/20 | 0.84 |
| ▸ | RAB9A | P51151 | 1/20 | 0.84 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.84 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20357485 | 1.00 | NPC1 (0.84) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL31545545 | 1.00 | NPC1 (0.84) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL31545138 | 1.00 | NPC1 (0.84) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL26218683 | 1.00 | NPC1 (0.84) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28042224 | 1.00 | NPC1 (0.84) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL11187337 | 1.00 | NPC1 (0.84) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL27693672 | 0.98 | HTT (0.88) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL18782422 | 0.96 | HTT (0.92) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL20477532 | 0.96 | HTT (0.92) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL5881393 | 0.94 | NPC1 (0.74) | NPC1HPGDMAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285472-A1 | PSEUDOMONAS CHLORORAPHIS SPECIES AND ITS USE IN THE CONTROL OF FISH DISEASES CAUSED BY BACTERIA AND FUNGI | T3 BIOSCIENCE, INC. | 2023-09-14 | — | — | US | disclosed |
| US-20230285472-A1 | PSEUDOMONAS CHLORORAPHIS SPECIES AND ITS USE IN THE CONTROL OF FISH DISEASES CAUSED BY BACTERIA AND FUNGI | T3 BIOSCIENCE, INC. | 2023-09-14 | — | — | US | disclosed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| WO-2022165169-A1 | PSEUDOMONAS CHLORORAPHIS SPECIES AND ITS USE IN THE CONTROL OF DISEASES CAUSED BY BACTERIA AND FUNGI | T3 Bioscience, LLC (US) | 2022-08-04 | — | — | WO | disclosed |
| US-20220232834-A1 | PSEUDOMONAS CHLORORAPHIS SPECIES AND ITS USE IN THE CONTROL OF DISEASES CAUSED BY BACTERIA AND FUNGI | T3 BIOSCIENCE, INC. | 2022-07-28 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220232834-A1 | PSEUDOMONAS CHLORORAPHIS SPECIES AND ITS USE IN THE CONTROL OF DISEASES CAUSED BY BACTERIA AND FUNGI | PGAM1, PMM2, PGLS | NPC1 2409/4885HPGD 3871/4885MAPK1 2310/4885 |
| US-20230285472-A1 | PSEUDOMONAS CHLORORAPHIS SPECIES AND ITS USE IN THE CONTROL OF FISH DISEASES CAUSED BY BACTERIA AND FUNGI | PF4, IL4, ACLY | NPC1 1882/4885HPGD 4130/4885MAPK1 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.