SCHEMBL9745513

SCHEMBL9745513

CCCCc1c(O)cc(CCC)cc1O

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.88
NPC1 O15118 1/20 0.88
HPGD P15428 1/20 0.88
MAPK1 P28482 1/20 0.88
RAB9A P51151 1/20 0.88
NPSR1 Q6W5P4 1/20 0.88
CNR1 P21554 3/20 0.50
CNR2 P34972 3/20 0.50
KDM4E B2RXH2 1/20 0.50
PKM P14618 1/20 0.50
PTGS2 P35354 3/20 0.47
CYP3A4 P08684 1/20 0.47
CYP19A1 P11511 1/20 0.44
ALDH1A1 P00352 1/20 0.44
IAPP P10997 1/20 0.43
TRPV1 Q8NER1 2/20 0.43
TRPA1 O75762 1/20 0.43
INHA P05111 1/20 0.43
SLC6A2 P23975 1/20 0.43
HTR2A P28223 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9744288 0.93 HTT (1.00) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL27930400 0.93 NPC1 (0.91) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL5881393 0.92 NPC1 (0.74) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL9743684 0.91 NPC1 (0.88) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL18782422 0.89 HTT (0.92) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL20477532 0.89 HTT (0.92) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL1179405 0.89 HTT (0.68) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL27693672 0.87 HTT (0.88) HTTNPC1HPGDMAPK1RAB9A
SCHEMBL9744115 0.87 NPC1 (0.80) HTTNPC1HPGDMAPK1RAB9A
Resorstatin SCHEMBL17867326 0.85 NPC1 (0.84) HTTNPC1HPGDMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 US disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed