Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | NT5E | P21589 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032113 | 0.88 | NT5E (0.85) | MAPTMEN1KMT2AMAPK1NT5E | |
| SCHEMBL10765820 | 0.85 | NT5E (0.55) | MAPTMEN1KMT2AMAPK1NT5E | |
| SCHEMBL10758831 | 0.84 | NT5E (0.51) | MAPTMEN1KMT2AMAPK1NT5E | |
| SCHEMBL10760475 | 0.84 | NT5E (0.57) | MAPTMEN1KMT2AMAPK1NT5E | |
| SCHEMBL10761714 | 0.83 | CYP3A4 (0.55) | MAPTMEN1KMT2AMAPK1NT5E | |
| SCHEMBL10762587 | 0.83 | NT5E (0.50) | MAPTMEN1KMT2AMAPK1NT5E | |
| SCHEMBL9878142 | 0.82 | NT5E (0.61) | MAPTMEN1KMT2AMAPK1NT5E | |
| SCHEMBL9744729 | 0.82 | NT5E (0.61) | MAPTMEN1KMT2AMAPK1NT5E | |
| SCHEMBL19262229 | 0.81 | NT5E (0.48) | MAPTMEN1KMT2AMAPK1NT5E | |
| SCHEMBL10764748 | 0.80 | TDP1 (0.58) | MAPTMEN1KMT2AMAPK1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212412-B1 | POLYAZO DYES | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0212412-A2 | Polyazo dyes | BAYER AG (DE) | 1987-03-04 | — | — | EP | disclosed |