Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032113 | 0.84 | NT5E (0.85) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9744302 | 0.82 | MAPT (0.66) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9879008 | 0.80 | CYP19A1 (0.42) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9877920 | 0.80 | CYP19A1 (0.44) | MAPTMAPK1TDP1TBXA2RALDH1A1 | |
| SCHEMBL10401803 | 0.80 | MAPT (0.59) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9877591 | 0.79 | ALDH1A1 (0.49) | NT5EKDM4EGAATDP1ALDH1A1 | |
| SCHEMBL9744729 | 0.79 | NT5E (0.61) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9878201 | 0.77 | KAT2B (0.46) | MAPTKMT2AGAATDP1ALDH1A1 | |
| SCHEMBL28375987 | 0.76 | NT5E (1.00) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL10702427 | 0.76 | NT5E (0.71) | NT5EMAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |