SCHEMBL9744447

SCHEMBL9744447

O[SiH2]CCCCCCCCCC(c1cccc2ccccc12)(c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 2/20 0.36
KIF11 P52732 1/20 0.35
CYP1A2 P05177 1/20 0.32
HPRT1 P00492 1/20 0.31
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HPGD P15428 2/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
TSHR P16473 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3786885 0.79 ACP3 (0.36) ACP3KIF11CYP1A2HPRT1HPGD
SCHEMBL1818271 0.75 KCNA3 (0.35) ACP3KIF11TDP1
SCHEMBL624788 0.71 ACP3 (0.35) ACP3KIF11CYP1A2KDM4EHPGD
SCHEMBL31516172 0.71 ACP3 (0.35) ACP3KIF11CYP1A2KDM4EHPGD
SCHEMBL8019682 0.71 ACP3 (0.39) ACP3KIF11CYP1A2HPRT1KDM4E
SCHEMBL20483733 0.70 ACP3 (0.36) ACP3MEN1KMT2AALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL15094349 0.70 ACP3 (0.35) ACP3KIF11CYP1A2KDM4EHPGD
Tetrabuthylammonium SCHEMBL11969818 0.68 CHAT (0.33) CYP1A2KDM4EMEN1KMT2AHPGD
Tetramethylammonium Ion SCHEMBL1146977 0.67 ACP3 (0.33) ACP3KIF11CYP1A2KDM4EMEN1
SCHEMBL20483656 0.66 ALDH1A1 (0.36) ACP3KIF11CYP1A2HPRT1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5099006-A ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates RHONE-POULENC INC. (US) 1992-03-24 US disclosed
EP-0324671-A2 Alkoxy-type derivatives of trivalent metals of group 3b, and their preparation RHONE-POULENC CHIMIE (FR) 1989-07-19 EP disclosed
EP-0319383-A2 Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed
EP-0319384-A2 Cerium hydrocarbonsilyloxydes and process for their manufacture RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed