Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400033 | 0.82 | HTT (0.52) | HTTNPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL10552954 | 0.81 | HTT (0.51) | HTTNPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL9503246 | 0.81 | MEN1 (0.47) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL17847847 | 0.76 | HTT (0.51) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL10554694 | 0.76 | P2RX7 (0.43) | HTTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL9745131 | 0.76 | ALDH1A1 (0.35) | HTTNPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL27278396 | 0.76 | HTT (0.67) | HTTNPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL27676260 | 0.75 | HTT (0.66) | HTTNPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL9744533 | 0.74 | HTT (0.44) | HTTNPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL11055051 | 0.74 | MAPK1 (0.50) | HTTNPC1RAB9ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268800-B1 | PHENOXYACETIC ACID DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1992-02-05 | — | — | EP | disclosed |
| US-4853404-A | DIURETIS, SALURETICS, URICOSURETICS | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0268800-A1 | Phenoxyacetic acid derivatives and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-01 | — | — | EP | disclosed |