SCHEMBL9744485

SCHEMBL9744485

Oc1ccc(CCc2ccccc2)cc1O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.84
IGF1R P08069 4/20 0.84
IDH1 O75874 1/20 0.69
DRD1 P21728 3/20 0.66
SLC6A2 P23975 3/20 0.66
DRD3 P35462 3/20 0.66
SLC6A3 Q01959 3/20 0.66
ADRB2 P07550 2/20 0.66
ADRA1A P35348 2/20 0.66
ADORA3 P0DMS8 1/20 0.66
CHRM1 P11229 1/20 0.66
ADRA2B P18089 1/20 0.66
ADRA2C P18825 1/20 0.66
SLC6A4 P31645 1/20 0.66
PTGS2 P35354 1/20 0.66
HRH1 P35367 1/20 0.66
OPRK1 P41145 1/20 0.66
PDE4D Q08499 1/20 0.66
KCNH2 Q12809 1/20 0.66
HRH3 Q9Y5N1 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2306276 0.91 ALOX15 (1.00) ALOX15IGF1RIDH1DRD1SLC6A2
SCHEMBL8431254 0.91 ALOX15 (0.76) ALOX15IGF1RDRD1SLC6A2DRD3
Carbon Dioxide SCHEMBL10411957 0.90 ALOX15 (0.70) ALOX15IGF1RIDH1DRD1SLC6A2
SCHEMBL30631592 0.88 ALOX15 (0.80) ALOX15IGF1RDRD1SLC6A2DRD3
SCHEMBL107956 0.88 ALOX15 (0.80) ALOX15IGF1RDRD1SLC6A2DRD3
SCHEMBL10908415 0.86 ADRB2 (0.87) ALOX15IGF1RIDH1DRD1SLC6A2
SCHEMBL6049241 0.85 IGF1R (0.68) ALOX15IGF1RIDH1DRD1SLC6A2
SCHEMBL10613049 0.84 ALOX15 (0.62) ALOX15IGF1RIDH1DRD1SLC6A2
SCHEMBL28999489 0.84 ALOX15 (0.83) ALOX15IGF1RDRD1SLC6A2DRD3
SCHEMBL9487127 0.83 ALOX15 (0.60) ALOX15IGF1RIDH1DRD1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0290442-A4 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS. CHEMEX PHARMACEUTICALS INC (US) 1990-07-03 EP claimed
EP-0290442-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-11-17 EP claimed
WO-1988003805-A1 PHARMACOLOGICALLY ACTIVE COMPOUNDS AND MIXTURES THEREOF, ORGANIC COMPOSITIONS AND METAL SALTS CHEMEX PHARMACEUTICALS, INC. (US) 1988-06-02 WO claimed
CN-110121330-A Personal care compositions with glutathione precursors comprising 4-substituted resorcinols and amino acids 荷兰联合利华有限公司 2019-08-13 CN disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed
US-4345019-A Diffusion transfer process MITSUBISHI PAPER MILLS, LTD. (JP) 1982-08-17 US disclosed