Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9092970 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2CTSDMAPTPOLB | |
| SCHEMBL10422232 | 0.81 | ITGB1 (0.36) | ALDH1A1L3MBTL1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL2289848 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2CTSDMAPTHTT | |
| SCHEMBL28842777 | 0.73 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1SMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7108168 | 0.73 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2CTSDMAPTHTT | |
| SCHEMBL9647951 | 0.73 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2CTSDMAPTHTT | |
| SCHEMBL9647959 | 0.72 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2CTSDMAPT | |
| SCHEMBL9647969 | 0.72 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2CTSDMAPT | |
| SCHEMBL31542074 | 0.71 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1SMN1; SMN2CTSDMAPT | |
| SCHEMBL1670667 | 0.71 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1SMN1; SMN2CTSDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138088-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-11 | — | — | US | claimed |
| US-4965396-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1990-10-23 | — | — | US | claimed |
| US-5138088-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-11 | — | — | US | disclosed |
| US-5138088-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-11 | — | — | US | disclosed |
| US-5138088-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1992-08-11 | — | — | US | disclosed |
| US-4965396-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1990-10-23 | — | — | US | disclosed |
| US-4965396-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1990-10-23 | — | — | US | disclosed |
| US-4965396-A | Nitrobenzoyl-3-cyclopropylaminoacrylates and a process for the preparation thereof | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1990-10-23 | — | — | US | disclosed |