Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744500 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CTSDKMT2ASMN1; SMN2MAPT | |
| SCHEMBL2289848 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CTSDKMT2AGAASMN1; SMN2 | |
| SCHEMBL9647951 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CTSDKMT2AGAASMN1; SMN2 | |
| SCHEMBL7108165 | 0.74 | ALDH1A1 (0.58) | ALDH1A1CTSDKMT2AGAASMN1; SMN2 | |
| SCHEMBL9647959 | 0.73 | ALDH1A1 (0.56) | ALDH1A1CTSDKMT2AGAASMN1; SMN2 | |
| SCHEMBL9647969 | 0.73 | ALDH1A1 (0.56) | ALDH1A1CTSDKMT2AGAASMN1; SMN2 | |
| SCHEMBL1706209 | 0.71 | CTSD (0.56) | ALDH1A1CTSDKMT2AGAASMN1; SMN2 | |
| SCHEMBL195311 | 0.71 | ALDH1A1 (0.62) | ALDH1A1CTSDKMT2AGAASMN1; SMN2 | |
| SCHEMBL27562993 | 0.71 | ALDH1A1 (0.54) | ALDH1A1CTSDKMT2AGAASMN1; SMN2 | |
| SCHEMBL6551442 | 0.70 | ALDH1A1 (0.61) | ALDH1A1CTSDKMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516927-A | 2-nitrobenzoyl-3-silyloxyaminoacrylate derivatives and method for the preparation of the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-05-14 | — | — | US | claimed |
| US-5516927-A | 2-nitrobenzoyl-3-silyloxyaminoacrylate derivatives and method for the preparation of the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-05-14 | — | — | US | disclosed |
| US-5516927-A | 2-nitrobenzoyl-3-silyloxyaminoacrylate derivatives and method for the preparation of the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-05-14 | — | — | US | disclosed |