Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326410 | 0.80 | CA2 (0.32) | CA2NR1I2 | |
| SCHEMBL7301168 | 0.78 | CA2 (0.40) | CA2TP53 | |
| SCHEMBL7303995 | 0.78 | CA2 (0.40) | CA2TP53 | |
| SCHEMBL9744900 | 0.74 | — | — | |
| SCHEMBL9747045 | 0.72 | — | — | |
| SCHEMBL7303252 | 0.72 | ALDH2 (0.37) | — | |
| SCHEMBL9325034 | 0.72 | GLS2 (0.35) | — | |
| SCHEMBL9766908 | 0.70 | ZDHHC7 (0.43) | CA2 | |
| SCHEMBL9325309 | 0.70 | LMNA (0.42) | — | |
| SCHEMBL9746369 | 0.69 | ALDH2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0369811-A2 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |