Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 12/20 | 0.55 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771568 | 0.84 | ABCC1 (0.61) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL3026966 | 0.81 | ABCC1 (0.71) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL11773488 | 0.78 | CACNA1F (0.56) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL9744740 | 0.77 | CACNA1B (0.55) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL11526085 | 0.77 | ABCC1 (0.61) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL9502243 | 0.77 | ADORA3 (0.73) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL7266484 | 0.77 | CACNA1B (0.73) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL9675983 | 0.77 | ABCC1 (0.57) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL9745148 | 0.76 | ADORA3 (0.48) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S | |
| SCHEMBL11779267 | 0.76 | CACNA1B (0.65) | CACNA1BABCC1CACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215250-B1 | 2-SUBSTITUTED-1,4-DIHYDROPYRIDINES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-12-30 | — | — | EP | claimed |
| US-4845113-A | USEFUL IN RADICAL SCAVENGING THERAPY | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-07-04 | — | — | US | claimed |
| EP-0215250-B1 | 2-SUBSTITUTED-1,4-DIHYDROPYRIDINES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-12-30 | — | — | EP | disclosed |
| US-4845113-A | USEFUL IN RADICAL SCAVENGING THERAPY | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-07-04 | — | — | US | disclosed |