SCHEMBL1934741

SCHEMBL1934741

CCCCCCOc1ccc(OC(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.72
NPC1 O15118 3/20 0.72
NFKB1 P19838 3/20 0.72
NFKB2 Q00653 3/20 0.72
RELA Q04206 3/20 0.72
SMN1; SMN2 Q16637 3/20 0.72
NR5A1 Q13285 1/20 0.71
CYP1A2 P05177 2/20 0.70
CYP2D6 P10635 2/20 0.70
CYP2C19 P33261 2/20 0.70
CYP3A4 P08684 1/20 0.70
CYP2C9 P11712 1/20 0.70
TSHR P16473 2/20 0.63
TP53 P04637 1/20 0.63
MAPT P10636 2/20 0.62
LTA4H P09960 2/20 0.62
POLB P06746 1/20 0.62
PLA2G4B P0C869 1/20 0.61
PRSS1 P07477 1/20 0.61
ACR P10323 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9647625 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA
SCHEMBL1532142 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA
SCHEMBL5482347 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA
SCHEMBL9744746 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA
SCHEMBL5185777 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA
SCHEMBL9650301 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA
SCHEMBL11315675 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA
SCHEMBL8943247 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA
SCHEMBL9737668 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA
SCHEMBL27974007 1.00 LMNA (0.72) LMNANPC1NFKB1NFKB2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9449732-B2 Charge transport film, method for producing the same, and light-emitting element and photoelectric conversion element using the same FUJIFILM CORPORATION (JP) 2016-09-20 US disclosed
EP-2507851-A1 CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME FUJIFILM Corporation (JP) 2012-10-10 EP disclosed
US-20120238774-A1 CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
WO-2011068232-A1 CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME FUJIFILM CORPORATION (JP) 2011-06-09 WO disclosed
US-5395910-A Photostable polymers AKZO NOBEL N.V. (NL) 1995-03-07 US disclosed
EP-0550105-A2 Liquid-crystalline polyurethanes, compositions of said liquid-crystalline polyurethanes, and a device for optical data storage comprising a liquid-crystalline polyurethane Akzo Nobel N.V. (NL) 1993-07-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238774-A1 CHARGE TRANSPORT FILM, METHOD FOR PRODUCING THE SAME, AND LIGHT-EMITTING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT USING THE SAME PCTP, CDH1, PLTP LMNA 1221/4885NPC1 624/4885NFKB1 4784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.