Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719703 | 0.79 | POLB (0.33) | GAACYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL9744937 | 0.77 | MAPT (0.33) | CYP3A4CYP2C9CYP2C19MAPTCYP2D6 | |
| SCHEMBL9792736 | 0.72 | MGAM (0.39) | GAACYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL10913361 | 0.72 | MGAM (0.39) | GAACYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL10998341 | 0.71 | MGAM (0.38) | GAACYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL9744920 | 0.70 | CYP2D6 (0.43) | CYP2C9CYP2C19CYP2D6TSHR | |
| SCHEMBL10977480 | 0.69 | TSHR (0.37) | GAACYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL5390684 | 0.68 | POLB (0.42) | GAACYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL5390677 | 0.68 | POLB (0.42) | GAACYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL11013207 | 0.68 | LMNA (0.40) | GAACYP3A4CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175344-A | Anticonvulsants, anxiolytic agents | CIBA-GEIGY CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| EP-0233154-B1 | UNSATURATED AMINO-ACIDS | CIBA-GEIGY AG (CH) | 1991-12-18 | — | — | EP | disclosed |
| US-5051413-A | For treatment of ischemia, antispasmodic agents, anticonvulsants and anxiety or manic conditions | CIBA-GEIGY CORPORATION (US) | 1991-09-24 | — | — | US | disclosed |