⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451219 | 0.81 | — | — | |
| SCHEMBL17491874 | 0.79 | MAPT (0.47) | — | |
| SCHEMBL17451260 | 0.78 | — | — | |
| SCHEMBL14937116 | 0.77 | — | — | |
| SCHEMBL1706440 | 0.76 | MAPT (0.31) | — | |
| SCHEMBL7738883 | 0.75 | — | — | |
| SCHEMBL8979258 | 0.75 | — | — | |
| SCHEMBL10469608 | 0.75 | ACHE (0.32) | — | |
| SCHEMBL8383945 | 0.74 | — | — | |
| SCHEMBL6063729 | 0.73 | TET2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084537-A | Contact lenses from organosilicon monomers that are oxygen permeable | BAUSCH & LOMB, INCORPORATED (US) | 1992-01-28 | — | — | US | disclosed |
| US-5002979-A | Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent | BAUSCH & LOMB INCORPORATED (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0215817-B1 | CONTINUOUS-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0211067-B1 | OXYGEN-PERMEABLE LENSES | Bausch & Lomb Incorporated (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4829137-A | Continuous-wear highly oxygen permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1989-05-09 | — | — | US | disclosed |
| EP-0215817-A1 | CONTINUOUS-WEAR LENSES. | BAUSCH & LOMB (US) | 1987-04-01 | — | — | EP | disclosed |
| EP-0211067-A1 | OXYGEN-PERMEABLE LENSES. | BAUSCH & LOMB (US) | 1987-02-25 | — | — | EP | disclosed |
| EP-0209597-A1 | EXTENDED-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1987-01-28 | — | — | EP | disclosed |
| WO-1986004342-A1 | OXYGEN-PERMEABLE LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |
| WO-1986004341-A1 | CONTINUOUS-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |
| WO-1986004343-A1 | EXTENDED-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | disclosed |